Buy 2ethylhexyl 4methoxycinnamate cas 5466773, a uv induced cyclobutane pyrimidine dimer cdp formation inhibitior, from santa cruz. Dose reconstruction of di2ethylhexyl phthalate using a simple pharmacokinetic model article pdf available in environmental health perspectives 12012 september 2012 with 24 reads. Effects of di 2 ethylhexyl phthalate dehp on female fertility and adipogenesis in c3hn mice. However, only seven of the 21 target chemicals were detected, with di. It is the diester of 2ethylhexanol and adipic acid. Deha is sometimes called dioctyl adipate, incorrectly. Most substantial phthalate in the environment is di 2 ethylhexyl phthalate dehp. Dioctyltin bis2ethylhexyl thioglycolate, cas number. Dioctyltin bis 2 ethylhexyl thioglycolate chemical information, properties, structures, articles, patents and more chemical data.
The presence of 2 ethylhexyl acrylate can improve the water resistance, weatherability, and sunlight resistance of the final product. This fact sheet is one in a series of summaries about hazardous substances and their health effects. Postshift urine concentrations were generally higher than preshift concentrations for svoc metabolites. Linear doseresponse relationships were observed for induction of cyanideinsensitive palmitoyl coa oxidation pco, used as a enzyme marker of peroxisome proliferation, by deha, eh and eha in both. About ewg verified beyond providing skin deep as an educational tool for consumers, ewg offers its ewg verified mark as a quick and easily identifiable way of conveying personal care products that meet ewgs strict health criteria. This product can expose you to di 2 ethylhexyl phthalate dehpand other chemicals which are known to the state of california to cause cancer andor other developmental reproductive health issues. Biomonitoring of di2ethylhexyl phthalate dehp exposure. It is used in the solvent extraction of uranium, as well as the rareearth metals. Peroxisome proliferation due to di 2ethylhexyl adipate. Di 2 ethylhexyl phthalate dehp is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. Bis2ethylhexyl adipate or deha is an organic compound with the formula ch 2 ch 2 co 2 c 8 h 17 2.
The effects of the peroxisome proliferators di isononyl phthalate dinp and di 2 ethylhexyl phthalate dehp were evaluated in young adult male cynomolgus monkeys after 14 days of treatment, with emphasis on detecting hepatic and other effects seen in rats and mice after treatment with high doses of phthalates. Imagine a global collaborative knowledge base for original thoughts. Specifications acid number, mg kohg 280 330 color, apha 250 max. This fact sheet answers the most frequently asked health questions faqs about di2ethylhexyl phthalate dehp. Di 2 ethylhexyl phthlate dehp is a manufactured chemical that is commonly added to plastics to make them flexible. Di 2 ethylhexyl phthalate dehp was found by the national toxicology program ntp to be a hepatocarcinogen in f344 rats and b6c3f1 mice kluwe et al. Di 2 ethylhexyl dehp, di nbutyl dbp, and benzyl butyl bbp phthalate have shown reproductive effects in male laboratory animals. The exposure of the general population to phthalates is of increasing public health concern. Dehp is noncovalently bound to plastics, and therefore, it will leach out of these products after repeated use, heating, andor cleaning of the products.
The 3d structure may be viewed using java or javascript. Search thousands of articles and collaborate with scientists around the globe. The worlds first wiki where authorship really matters nature genetics, 2008. The migration of plastic components or additives from packaging to food can produce a risk for human health, in fact many of these plasticizers and additives are endocrine distruptors, such as phthalates paes, alkylphenols aps, 2, 2 bis4hydroxyphenylpropane bisphenol a or bpa and di 2 ethylhexyl adipate deha. Di 2 ethylhexyl azelate may undergo direct photolysis in the environment, since this compound contains a functional group that can absorb light 290 nm. Disclosed is a process for the preparation of di 2 ethylhexyl terephthalate by the esterification of terephthalic acid with 2 ethylhexanol at elevated temperature and pressure while the water of reaction is removed from the reaction mixture. There is a need to determine the noncarcinogenic effects based on the widespread use of dehp as a plasticizer. Other pertinent literature is also presented, but is described in less detail than the key studies. For more information, call the atsdr information center at 18884228737. Bis2ethylhexyl phthalate is an organic compound with the formula c6h4 2. Buy high purity bis2ethylhexyl terephthalate analytical standards from chem service inc.
Linear doseresponse relationships were observed for induction of cyanideinsensitive palmitoyl coa oxidation pco, used as a enzyme marker of peroxisome proliferation, by deha, eh and eha in both species. This public health statement tells you about di2 ethylhexyl phthalate dehp and the effects of exposure. Di2ethylhexyl phthalate dehp is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal. Dehp is present in plastic products such as wall coverings, tablecloths, floor tiles, furniture upholstery, shower curtains, garden hoses, swimming pool liners, rainwear, baby pants, dolls, some toys, shoes, automobile upholstery.
This table is not an exhaustive list, and current regulations should be verified by the appropriate regulatory agency. Bis2ethylhexyl phthalate di 2ethylhexyl phthalate, diethylhexyl phthalate, dehp. If released to soil, di 2 ethylhexyl azelate is expected to be immobile based upon an estimated koc of 300,000. Limited human health and environmental toxicity data were identified for doz. First check the victim for contact lenses and remove if present. The substance identity section is calculated from substance identification information from all echa databases. Di 2ethylhexyl adipate deha was of low acute toxicity in laboratory animals by the oral and dermal routes, although high oral doses affected the central nervous system of guineapigs. Chronic toxicity of di2ethylhexylphthalate in mice.
Using a structure estimation method based on molecular connectivity indices1, the koc for di 2 ethylhexyl azelate can be estimated to be 300,000src. Search results for di 2 ethylhexyl peroxydicarbonate at sigmaaldrich. It exhibits low toxicity from acute shortterm and chronic longterm. Infocards are automatically generated based on industry data. Please see the following for information about the library and its accompanying search program. Sixteen packed lunches and ten set lunches were analysed, and in all samples the concentration of di 2 ethylhexyl phthalate dehp was the highest, at 0. Sections i health hazard assessments for noncarcinogenic effects and. Why am i being warned about potential exposure to dehp. Diethylhexyl maleate skin deep cosmetics database ewg.
Di2ethylhexyl phthalate in the fruits of benincasa. Search results for di2ethylhexylperoxydicarbonate at sigmaaldrich. Di2ethylhexyl adipate migration from pvccling film into. Photoisomerization of 2ethylhexylpmethoxycinnamate by. The atsdr toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in. Adipic acid di 2 ethylhexyl ester, doa cas number 103231. According to a classification scheme 2, this estimated koc value suggests that di 2 ethylhexyl azelate is expected to be immobile in soil. Di 2 ethylhexyl phthalate dehp is a commonly used plasticizer that is harmful to human health. Due to the overuse of dehp in many products, it enters and. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910. Use bis 2 ethylhexyl chlorendate95 for fast, easy, and consistent dnarna purification, antibodyprotein purification, cell isolation. Di2ethylhexylphosphoric acid dehpa or hdehp is an organophosphorus compound with the formula c 8 h 17 o 2 po 2 h. Dehp is the most common member of the class of phthalates, which are used as plasticizers.
N,nbis2ethylhexyl5methyl1hbenzotriazole1methylamine. Import data and price of bis 2 ethylhexyl under hs code 2917. A sensitive and selective gcms method was developed and used for simultaneous analysis of di 2 ethylhexyl adipate deha and 20 selected phthalates in the food samples from the 20 canadian total diet study. Zinc, biso,obis2ethylhexyl phosphorodithioatokappas. Flush victims eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Each notification may be associated with multiple companies. Use molybdenum,biso,obis 2 ethylhexyl phosphorodithioato. Selected foods 260 samples packaged in materials with the potential to contribute plasticizers to the food, and available food composites 98 samples obtained from the canadian health protection branch total diet program, were analysed for phthalate plasticizers and di. Dioctyl terephthalate bis 2 ethylhexyl benzene1,4dicarboxylate or di 2 ethylhexyl terephthalate, commonly abbreviated dotp or deht, is an organic compound with the formula c 6 h 4 co 2 c 8 h 17 2.
When heated to decomposition it emits acrid smoke and irritating fumes. Food intake, weight gain, fat storage, and fertility in mice. Establishing an allowable level for di 2 ethylhexyl phthalate in bottled water may 2012 download the final guidance document read the federal register notice final. It is a nonphthalate plasticizer, being the diester of terephthalic acid and the branchedchain 2. Recommendation for dinoctyltin bis2 ethylhexyl maleate usage levels up to. Di2ethylhexylphthalate dehp proposition 65 warnings website. Wikigenes dehp bis2ethylhexyl benzene1,2dicarboxylate. Bis2ethylhexyl phthalate also known as di2ethylhexyl phthalate or dehp, a branchedchain dioctyl ester of phthalic acid, is the most. It is soluble in ethanol and other hydrocarbon solvents. Octyl methoxycinnamate or ethylhexyl methoxycinnamate or octinoxate, trade names eusolex 2292 and uvinul mc80, is an organic compound that is an ingredient in some sunscreens and lip balms. Polyvinyl chloride pvc film containing di2ethylhexyl adipate deha plasticizer was used to wrap sea bream sparus aurata and rainbow trout oncorhynchus mykiss fillet samples with and without skin.
Peroxisome proliferation due to di 2ethylhexyl adipate, 2. Certain materials may be made available for download from the echa website such as lists, search results, committee. The doseresponse relationships for peroxisome proliferation due to di 2 ethylhexyl adipate deha, 2 ethylhexanol eh, 2 ethylhexanoic acid eha have been investigated in rats and mice. Buy high quality bis 2 ethylhexyl azelate 10324 2 from toronto research chemicals inc.
Biso,odi2ethylhexylthiophosphonyldisulfide substance. Phthalates are everywhere, and a tidal wave of new research has. Dehp is on the proposition 65 list because it can cause cancer. Explore information about air pollutants, contaminants and studies being done. Pdf dose reconstruction of di2ethylhexyl phthalate using. It can be polymerized by itself or in combination with other acrylic monomers. Compound di 2 ethylhexyl azelate with free spectra. Migration of phthalates, alkylphenols, bisphenol a and di. Pertinent international and national regulations, advisories, and guidelines regarding dehp in air, water, and other media are summarized in table 71. Di2ethylhexyl adipate and 20 phthalates in composite. In order to address data gaps for specific hazard endpoints.
Dnbp, di2ethylhexyl phthalate dehp, diethyl phthalate dep, dibutyl. Atsdr toxic substances di2ethylhexylphthalate dehp. Adipic acid di2ethylhexyl ester, doa cas number 103231. Archived bis2ethylhexyl phthalate management of toxic. Use of the information, documents and data from the echa website is subject to the terms and conditions of this legal notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the echa website may be reproduced, distributed andor used, totally or in part, for noncommercial purposes provided that echa is. Recommendation for dinoctyltin bis2 ethylhexyl maleate flavor usage levels up to. Structure, properties, spectra, suppliers and links for. The absorption and metabolism of di 2 ethylhexyl terephthalate were studied by administering hexyl14c di 2 ethylhexyl terephthalate in corn oil by oral gavage at a dose level of 100 mgkg to 10 adult male sprague dawley rats. Mar 03, 2011 di 2 ethylhexyl phthlate dehp is a manufactured chemical that is commonly added to plastics to make them flexible. Download scientific diagram photoisomerization of 2ethylhexylp methoxycinnamate by irradiation of sunlight.
All mass spectra in this site plus many more are available from the nistepanih mass spectral library. Compound di 2 ethylhexyl adipate with free spectra. Download our flavors and fragrances catalog to view our entire product line. Di2ethylhexyl phthalate contamination of retail packed. Bis2ethylhexyl phthalate di2ethylhexyl phthalate, diethylhexyl phthalate, dehp. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the molecular and structural formulas. Sebacic acid, bis2ethylhexylester bis2 ethylhexyl sebacate decanedioic acid, bis2ethylhexyl ester dioctyl sebacate. Band gap and molecular energy level control of perylene diimidebased donoracceptor copolymers for allpolymer solar cells. Public health statement di2ethylhexylphthalate dehp. Band gap and molecular energy level control of perylene. Bis2ethylhexyl phthalate dehp is used in the production of polyvinyl chloride pvc. Bis 2 ethylhexyl ether 10143609 buy and find out price and availability, msds, properties of tcis high quality specialty chemicals.
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